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The ratio of fluorescence amplitudes gives the ion concentration Organelle marking experiments using dyes that label specific organelles and cytoskeletal proteins Determination of the rates and extents of enzyme reactions using conjugates of fluorochromes whose fluorescence changes due to enzymatic activity Study of cell viability and the effects of factors that influence the rate of apoptosis in cells using a combination of dyes that are permeant and impermeant to the plasma membrane Examination of cell functions such as endocytosis, exocytosis, signal transduction, and the generation of transmembrane potentials using fluorescent dyes..

Finally, the similarity of two documents Si and Sj can be expressed as a cosine relationship (cosine coef cient):

The listing of a computer program called ICIMPGV used to compute the parasitic capacitances and inductances for the multilevel parallel interconnections on the GaAs-based high-density ICs and based on the numerical technique presented above is included in Appendix 2.2 on the accompanying ftp site. In the next two sections, the program ICIMPGV has been used to study the dependences of the interconnection capacitances and inductances on the various interconnection parameters. 2.7.6 Parametric Dependence of Interconnection Capacitances

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Gordon, CM, Dougherty, DD, Rauch, SL, Emans, SJ, Grace, E, Lamm, R, Alpert, NM, Majzoub, JA & Fischman, AJ (2000) Neuroanatomy of human appetitive function: a positron emission tomography investigation International Journal of Eating Disorders, 27, 163 171 Gordon, I, Lask, B, Bryant-Waugh, R, Christie, D & Timimi, S (1997) Childhood-onset anorexia nervosa: towards identifying a biological substrate International Journal of Eating Disorders, 22, 159 165 Hadigan, CM, Walsh, BT, Buttinger, C & Hollander, E (1995) Behavioural and neuroendocrine responses to meta-CPP in anorexia nervosa Biological Psychiatry, 37, 504 511 Halmi, KA, Eckert, E, LaDu, TJ & Cohen, J (1986) Anorexia nervosa: treatment ef cacy of cyproheptadine and amitriptyline Archives of General Psychiatry, 43, 177 181 Herholz, K, Krieg, JC, Emrich, H.

M, Pawlik, G, Bell, C, Pirke, KM, Pahl, JJ, Wagner, R, Wienhard, K, Ploog, D & Heiss, WD (1987) Regional cerebral glucose metabolism in anorexia nervosa measured by positron emission tomography Biological Psychiatry, 22, 43 51 Husain, MM, Black, KJ, Doraiswamy, PM, Shah, SA, Rockwell, WJK, Ellinwood, EH & Krishan, KR (1992) Subcortical brain anatomy in anorexia and bulimia Biological Psychiatry, 31, 735 738 Jimerson, DC, Lesem, MD, Kaye, WH & Brewerton, TD (1992) Low serotonin and dopamine metabolite concentration in cerebrospinal uid from bulimic patients with frequent binge episodes Archives of General Psychiatry, 49, 132 138 Jimerson, DC, Wolfe, BE, Metzger, ED, Finkelstein, DM, Cooper, TB & Levine, JM.

FIGURE 5.5.15 MTF as function of number of paths (or sections) for vertical multisection (or multipath) interconnection.

(1997) Decreased serotonin function in bulimia nervosa Archives of General Psychiatry, 54, 529 534 Katzman, DK, Lambe, EK, Mikulis, DJ, Ridgley, JN, Goldbloom, DS & Zipursky, RB (1996) Cerebral gray matter and white matter volume de cits in adolescent girls with anorexia nervosa Journal of Pediatrics, 129, 794 803 Kaye, WH, Ballenger, JC, Lydiard, RB, Stuart, GW, Laraia, MT, O Neil, P, Fossey, MD, Stevens, V, Lesser, SC & Hsu, G (1990) CSF monoamine levels in normal weight bulimia: evidence for abnormal noradrenergic activity American Journal of Psychiatry, 147, 225 229 Kaye, WH, Ebert, MH, Raleigh, M & Lake, R (1984) Abnormalities in CNS monoamine metabolism in anorexia nervosa Archives of General Psychiatry, 41, 350 355 Kaye, WH.

, Frank, GKW & McConaha, C (1999) Altered dopamine activity after recovery from restricting-type anorexia nervosa Neuropsychopharmacology, 21, 503 506 Kaye, WH, Frank, GK, Meltzer, CC, Price, JC, McConaha, CW, Crossan, PJ, Klump, KL & Rhodes, L (2001) Altered serotonin 2A receptor activity in women who have recovered from bulimia nervosa American Journal of Psychiatry, 158, 1152 1155 Kaye, WH, Gendall, KA, Fernstrom, MH, Fernstrom, JD, McConaha, CW & Weltzin, TE (2000) Effects of acute tryptophan depletion on mood in bulimia nervosa Biological Psychiatry, 47, 151 157 Kaye, WH, Greeno, CG, Moss, H, Fernstrom, J, Fernstrom, M, Lilenfeld, LR, Weltzin, TE & Mann, JJ.

(1998) Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa Archives of General Psychiatry, 55, 927 935 Kaye, WH, Gwirtsman, HE, Brewerton, TD, George, DT & Wurtman, RJ (1988b) Bingeing behavior and plasma amino acids: a possible involvement of brain serotonin in bulimia nervosa Psychiatry Research, 23, 31 43 Kaye, WH, Gwirtsman, HE, George, DT, Jimerson, DC & Ebert, MH (1988a) CSF 5-HIAA concentrations in anorexia nervosa: reduced values in underweight subjects normalise after weight restoration Biological Psychiatry, 23, 102 105 Kaye, WH, Gwirtsman, HE, George, DT & Ebert, MH (1991) Altered serotonin activity in anorexia nervosa after long-term weight restoration: does elevated cerebrospinal 5hydroxyindoleacetic acid level correlate with rigid and obsessive behavior Archives of General Psychiatry, 48, 556 562 Kaye, WH.

where t1 R C CL t2 R 2Cc C CL 4:1:2

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