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the other polysaccharide fermentations, the reader is referred to the aforementioned publications Xanthan gum is an extracellular polysaccharide produced by Xanthomonas campestris and is commercially the most important bacterial polysaccharide It has widespread applications as a viscosity-enhancing agent and stabilizer in the food, pharmaceutical, and petrochemical industries (Jeanes et al, 1976; Norton et al, 1981) Since the cost of downstream processing determines whether or not the manufacture of the gum is commercially feasible, a high product concentration (>25 g/L) is essential (Pace and Righelato, 1980; Galindo, 1994) Ever since xanthan gum was reported by Rogovin et al (1961), considerable research has been devoted to addressing the problems of poor bulk mixing and low oxygen transfer rates in xanthan gum fermentations (Moraine and Rogovin, 1973; Nienow, 1984; Funahashi et al, 1987a,b,c, 1988a,b; Nienow and Elson, 1988; Peters et al.

, 1989a,b, 1992; Galindo and Nienow, 1992, 1993; Herbst et al, 1992; Flores et al, 1994; Zhao et al, 1991, 1994) It is generally agreed in the literature that the process bottleneck in highly productive xanthan fermentations is related to these two parameters However, the interpretation of experimental results in relation to these problems is dif cult, due to the inability to separate the variable of oxygen transfer from that of vessel inhomogeneity Accumulation of the extracellular gum also induces rheological complexities such that zones of signi cant motion (called a cavern) around impellers are formed (Figure 18-13), with essentially stagnant regions elsewhere (Nienow and Elson, 1988; Amanullah et al, 1998a,b) Cavern size is governed by the properties of the uid, power input, and agitator design and is regarded as one of the limiting factors in the fermentation process.

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molybdenum grid is often slightly texturized to retain sputtered material to avoid flaking of the sputter-deposited material [411 The threshold voltage for the onset of field emission versus the gap spacing measured for molybdenum electrodes using a standard plate-and-ball test arrangement in a high vacuum facility [42] is shown in Fig 5-14 The data show a classic power-law dependence of the threshold voltage with gap spacing for small gaps, which is sometimes called the total voltage effect [43] While there are numerous possible mechanisms for the total-voltage effect, the increased gap reduces the surface electric field and the field emission current but increases the probability of an atom or particulate being ionized while traversing the gap The ionized atom or particle is then accelerated into the cathode potential electrode and produces secondary electrons If sufficient ionizations and secondary electrons are produced, the process cascades and the gap breaks down.

Thus, homogeneity of the broth is important to maintain optimal levels of dissolved oxygen, temperature, and pH and to prevent gradients in these parameters In addition, oxygen transfer becomes increasingly dif cult in these highly viscous broths..

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Cell phones are the devices of choice when communicating with employees who are not at their desks. This behavior will continue, but new channels will support it. Many people think that e-mail is the nail in mobile usage s coffin. But that isn t the case. In fact, there is no single killer application in the mobile enhancement of enterprise processes enterprise efficiency will be optimized as a result of combining different communication channels. Let s take a closer look at some of the technology surrounding messag ing so we can get away from the view of devices as mere message reposi tories. Messages will always reside in a central server. You can then synchronize and download messages to your mobile device or use a browser to view them. The key element is that you will use different devices all the time probably a PC when you are at your desk, a midsized PDA when you have just left your desk, and a smartphone when you are traveling. The increased speed in the wireless network will enable you to handle your messages almost as fast as when you are connected to a

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