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destructive, 64 Interline transfer CCD cameras, 267 268 Intrinsic birefringence, 127 Inverse transform diffraction patterns, 81 82 digital image processing, 299 Inverted microscopes, design of, 3 4, 11 Ion arc lamps, 30 33 IR-blocking filters, 40 Jablonski diagram, 180 Kalman averaging, 217 Koehler, August, 1, 7 9 Koehler illumination adjusting the microscope for, 7, 9 11 characteristics of, 6 7 DIC microscopy, 158 diffraction pattern formation, 80 modulation contrast microscopy, 172 phase contrast microscopy, 104 Laser(s) in confocal laser scanning microscopy, 221 light, 20 21 Lens equation, 46 47, 59 Lenses, see Objective lenses; Simple lenses aberrations, 50 52 object-image math, 46 50 Light intensity, see Intensity of light as probe, 15 18 properties, 18 22 Light microscopy aperture, 4 6 calibration of magnification, 12 13 handling precautions, 11 image planes, 4 6 inverted designs, 3 4 Koehler illumination, 6 10 oil immersion optics, 4, 11 optical components of, 1 3 Linearly polarized light, 21, 117, 119, 121 Live cells, examination of effects of light on, 32, 41 42 fluorescence microscopy, 198 203 Logarithmic histogram, 287 Long pass filters, 37 38 Long working distance lenses, 54 Look-up-table (LUT), digital image processing applications, generally, 284 287 exponential, 287 289 Low-pass filter, image processing, 293 Magnification calibration of, 12 13 defined, 1, 47 49 Maintenance guidelines, see Cleaning and maintenance guidelines Malus law, 124

We all have some degree of tremor on sustained posture, termed physiological tremor. This is faster than parkinsonian or cerebellar tremor, absent at rest, and most evident in the hands. Most of the predominantly postural tremors are due to an exaggeration of this phenomenon. Postural tremors are made more obvious when circulating catecholamines are increased, for example by anxiety, and by sympathomimetic drugs like salbutamol. Conversely, they are suppressed to some extent by beta-adrenergic blockade and sometimes by alcohol. The mechanisms of these effects are not understood. They are often exploited by people who require a steady hand, such as surgeons, snooker players or musicians, who may take propranolol or alcohol on important occasions. Reliance on alcohol to treat tremor can lead to dependency and liver disease. The most disabling postural tremor is familial essential tremor, which tends to be dominantly inherited. A more jerky, asymmetrical variant of essential tremor is seen in patients with a personal or family history of dystonia, and is referred to as dystonic tremor; it is less responsive to beta-blockers or alcohol.

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There is a great body of theory (although none completely conclusive) concerning the effectiveness of these real-time, virtual meetings It may now be apparent that the current performance of audio and video conferencing services is not yet up to the standard of a real meeting Nevertheless, they do offer a reasonable, low-cost solution for many purposes It is probably true to say that they reinforce collaboration rather than create trust, ab initio As such, they are very satisfactory for use by distributed project teams, who can be considered to have at least a minimum set of shared goals and purpose Audio is quite suf cient for routine progress meetings of this type; video may be required when a bit more empathy has to be generated or when design information has to be shared.

In the eBusiness context, we ought to be aware that in using these virtual environments that are intended to build trust and support empathy between the partners in the virtual enterprise, there can be a danger that arises from their tendency to create an informal atmosphere Open discussions and friendly feelings are essential, but they are not always structured and it is not always easy to recollect what exactly was agreed There will exist a need to make proper records of the meetings, usually in an electronic text Contractual negotiation is one case in point Another case of this is in call-centre operations where integration of the call data (time, number dialled, etc) can automatically be integrated with notes on the conversation typed in by the call-centre agent This, of course, captures only the minute-taker s perspective on what took place.

In a study on English sole it was shown that carcinogenic polycyclic aromatic hydrocarbons and their metabolites could accumulate in reproductive tissues and chemically modify gonadal macromolecules (DNA), and it has been shown in mammalian studies that this can lead to such effects as mutagenesis and teratogenesis (Varanasi et al, 1982) This, together with data reported in sections 21 to 23, demonstrates that there is evidence to indicate that the DNA of marine species can be affected by contaminants which in all probability would translate into some type of abnormality in the offspring, or death Several studies have demonstrated developmental abnormalities in n sh species which could result from direct toxicity or as a consequence of damage to the DNA.

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