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If you follow this guideline, dark gray values will not become swallowed up by black, and light gray values will not disappear and come out looking white..

2.3.3.5 Case Retrieval Each case obtained in Section 2.3.3.4 is a collection of fuzzy sets {fuzzsets} described by a set of one-dimensional p-membership functions with different c and l values. To compute the similarity of an unknown pattern ^ (of dimension n) to a case ep (of variable dimension np, np n), we use e s 1 Xnp SM ^; ep e mj Fj 2 j 1 fuzzset np

is called the Hartley information gain of A and B w.r.t. R. With this definition the connection of Hartley information gain to the relative number of possible value combinations becomes obvious: it is simply the binary logarithm of the reciprocal of this relative number. It is also clear that this definition can easily be extended to more than two attributes by adding factors to the product in the numerator and by extending the denominator. Note that Hartley information gain is zero if and only if the relative number of value combinations is one. Therefore the Hartley information gain is zero if and only if the considered attributes are relationally independent. If the attributes are dependent, it is the greater, the more strongly dependent the attributes are. Consequently, the Hartley information gain (or, equivalently, the relative number of possible value combinations) can be used directly to test for (approximate) marginal independence. This is demonstrated

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An alternative approach to understanding the genetic basis of eating disorders and obesity might be to search for genes involved in the control of body leanness (fat free mass) (Bjorntorp, 2001) Fat free mass (FFM) consists mostly of bone tissues and skeletal muscle and can be calculated from percent body fat A genome-wide linkage study has been conducted to identify candidate chromosomal regions for FFM In this study FFM showed signi cant linkage to a genetic marker within the insulin-like growth factor-1 receptor (IGF-1R) gene on chromosome 15q25 q26 and to two markers on chromosome 18q12 (Chagnon et al, 2000a) A moderately signi cant linkage was observed on chromosome 7p153, which contains a plausible candidate gene, the growth hormone-releasing hormone (GHRH) receptor gene These positive linkages need to be replicated in other populations.

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An association between a variant of the insulin-like growth factor-1 (IGF-1) gene and FFM has been reported (Sun et al, 1999) This IGF-1 gene variant has also been linked to the changes in FFM in response to 20 weeks of endurance exercise (Sun et al, 1999) The roles of variants of the IGF-1R, GHRH, IGF-1 genes in eating disorders and obesity need to be assessed in association studies Another approach to identify lean genes is to examine genetic variants in people that have managed to keep their bodyweight constant without dif culty These people are a rare, speci c subgroup who might have genetic variants that differ from the general population and that are protecting them from gaining weight.

In a study of women who have managed to keep their weight constant from the age of 21 years, a speci c variant of the aromatase gene, whose protein product functions more ef ciently, has been implicated in their ability to stay lean (Bjorntorp, 2001) The identi cation of such genes may provide targets for therapeutic intervention in obesity..

Assessments of decision-making have been criticised (Bursztajn et al., 1991) for focusing on cognition, with little attention on the role of emotional factors, except insofar as they de ne and are associated with a particular mental disorder. Examples include the negative views of the self, current experiences and the future, which characterise depression. (See section 5 of Gelder et al., 2000, and Grisso and Appelbaum, 1998, p. 53). In clinical practice, however, feelings of shame, guilt and low selfesteem are widely expressed by people with a range of conditions (for example, mental illness (British Psychological Society, 2000); intellectual disabilities (Jahoda et al., 1988; Sinason, 1992); dementia (Jacoby and Oppenheimer, 2002). It would not be surprising if these affected their ability to make decisions. Many such feelings are likely to re ect social factors.

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