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Does your proposed profile provide clear guidelines to salespeople Does it weed out few customers or identify a group that is inherently unsuitable for your value proposition and price point Can you see many customers fitting this profile in your current customer base How did they get there

Efficiently delivering TCP data over wireless links also requires cross-layer design approach. Conventional TCP regards packet loss as an indication of network congestion and, thus, decreases the transmission rate accordingly. However, delivering TCP packets over wireless links has different characteristics from the wired link. Packet loss due to bad channel conditions needs to be addressed differently from network congestion - the channel-quality-related packet loss should not incur the decrease of TCP transmission rate. One approach is to deploy ARQ and coding at a faster time scale than the TCP control loop [2]. Such a scheme hides T C P from the wireless links and the channel perceived by TCP layer is almost invariant. However, this approach loses capacity due to the extra effort put on the lower layers.

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7.3.2.6 Active Pharmaceutical Ingredients and Excipients Physicochemical Properties of APIs Hygroscopicity Hygroscopicity is the amount of moisture absorbed by a powder when it is exposed to an atmosphere of a known relative humidity. It is part of the preformulation program and its importance lies in the use of the information gained to decide whether or not a particular salt of the drug in question could be used for a dosage form design. Report has shown that urazepam is used as a monosulfate rather than the disulfate which however has many other desirable characteristics: It is so hygroscopic that it will remove water from a hard-shell capsule and then render it very brittle [64]. Knowledge of the hygroscopicity of the APIs can aid in the selection of packaging materials. Crystalline State or Amorphous State and Polymorphism Solid drug particles occur as pure crystalline substances of de nite indenti able shape or as amorphous particles without de nite structure. The energy required for a molecule of a drug to leave the lattice in a crystal is very much greater than the energy required in an amorphous powder. Drugs in the crystalline state have low reactivity. A linear relationship has been found between the solid-state degradation rate constant of various vitamin A derivatives and the inverse of the melting point [65]. Moreover, results of studies on the relationships between degradation rate and crystallinity of lactam antibiotics such as cefazolin indicate that a drug with low crystallinity tends to have decreased chemical stability [66].

could be handled It was something of a balancing act, meant to be done with only one hand A-Min picked up the bowl, gripping it and the lid together, and then he poured, alternating back and forth over the small cups in a seemingly random fashion until they were all lled to the brim We were each given a small cup of tea to drink A-Min slurped his tea in one go, deliberately leaving a few drops behind in the cup He tilted the cup to show me that it contained the dregs that were too ne to be ltered by the bowl s lid After tossing these into the tea tray with a ick of his wrist, he showed me the cup again so that I could see that it had been properly cleaned Just like any social ritual, there were subtleties.

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How someone poured tea or handled a cup, might hint at background, status, or personality type A-Min slid the tea tray over in my direction so that I might have a turn pouring I had been in his of ce enough to know that not everyone got this chance The leaves that were already in the bowl could be used again, so all I had to do was replenish the hot water and pour After picking up the small bowl and holding it by its edges with my thumb and ring nger, I positioned my right pinky on the bottom to lend support, while placing a sideways-positioned fore nger on top in order to hold the lid in place With my hand positioned just so like a stiffened claw I began to pour, but there was a problem.

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