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Wang, SS, and Good, TA (2001) Effect of culture in a rotating wall bioreactor on the physiology of differentiated neuron-like PC12 and SH-SY5Y cells J Cell Biochem 83: 574 584 Watson, DJ, Longhi, L, Lee, EB, Fulp, CT, Fujimoto, S, Royo, NC, Passini, MA, Trojanowski, JQ, Lee, VM, McIntosh, TK, Wolfe, JH (2003) Genetically modi ed NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury J Neuropathol Exp Neurol 62: 368 380 Weiss, C, Cahill, AL, Laslop, A, Fischer-Colbrie, R, Perlman, RL, Winkler, H (1996) Differences in the composition of chromaf n granules in adrenaline and noradrenaline containing cells of bovine adrenal medulla Neurosci Lett.

Likewise, practices that are detrimental to the effective functioning of the organization eventually affect individual wellbeing (Quick, Murphy, & Hurrell, 1992) Low productivity and high costs associated with organizational disease create threats to job security and potential deleterious effects of job loss (DeFrank & Ivancevich, 1986; Levi et al, 1984) It is therefore incumbent on practitioners to ensure that their programs provide value for their cost and ultimately improve the bottom line of the organization Apart from ethical standards, both public and private organizations are increasingly focused on data-driven, resultsbased programs and practices A competitive, global environment demands attention to the costs and bene ts of each business unit Private and government agencies are likewise held to performance standards and cost controls OHP practitioners have both professional and business stakes in the outcome of the programs and policies they recommend and implement.

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211: 29 32 Willing, AE, Othberg, AI, Saporta, S, Anton, A, Sinibaldi, S, Poulos, SG, Cameron, DF, Freeman, TB, Sanberg, PR (1999) Sertoli cells enhance the survival of co-transplanted dopamine neurons Brain Res 822: 246 250 Willing, AE, Sudberry, JJ, Othberg, AI, Saporta, S, Poulos, SG, Cameron, DF, Freeman, TB, Sanberg, PR (1999) Sertoli cells decrease microglial response and increase engraftment of human hNT neurons in the hemiparkinsonian rat striatum Brain Res Bull 48: 441 444 Willing, AE, Saporta, S, Lixian, J, Milliken, M, Poulos, S, Bowersox, SS, Sanberg, PR (2002) Preliminary study of the behavioral effects of LBS-neuron implantation on seizure susceptibility following middle cerebral artery occlusion in the rats Neurotoxicol Res.

4: 111 118 Winkler, C, Kirik, D, Bjorklund, A, Dunnett, SB (2000) Transplantation in the rat model of Parkinson s disease: ectopic versus homotopic graft placement Prog Brain Res 127: 233 265 Wong, DL (2003) Why is the adrenal adrenergic Endocr Pathol 14: 25 36 Yang, M, Donaldson, AE, Jiang, Y, Iacovitti, L (2003) Factors in uencing the differentiation of dopaminergic traits in transplanted neural stem cells Cell Mol Neurobiol 23: 851 864 Zigova, T, Barroso, LF, Willing, AE, Saporta, S, McGrogan, MP, Freeman, TB, Sanberg, PR (2000) Dopaminergic phenotype of hNT cells in vitro Brain Res Dev Brain Res 122: 87 90 Zigova, T, Song, S, Willing, AE, Hudson, JE, Newman, MB, Saporta, S, Sanchez-Ramos, J, Sanberg, PR.

To survive in this context, OHP practitioners and programs must demonstrate quantitative or qualitative measures of value to the organization Assessment, Surveillance, and Evaluation Occupational health psychologists engage in a range of roles and functions encompassing research, teaching, and practice (Adkins, 1999) Quantitative and qualitative information is the foundation for policy and practice decisions as well as a means for marketing principles and programs to organizational clients OHP is, in fact, a data-driven discipline The need for valid and reliable information on which to make policy and program decisions cuts across OHP data-based functions, domains of intervention, and factors associated with the organizational health process, as indicated in Figure 241..

(2002) Human umbilical cord blood cells express neural antigens after transplantation into the developing rat brain Cell Transplant 11: 265 274..

input output relationship could be nonlinear. This assumption broadens the implementation areas, especially in the chemical industry. However, it imposes challenges typical for nonlinear empirical models, such as unpredictable extrapolation, lack of model con dence limits, and multiplicity of model solutions. The second assumption is that the derived empirical model will guarantee reliable performance with acceptable accuracy of prediction inside the range of input data used for model development (also called training data). The excellent interpolation qualities of machine learning approaches, in general, and the universal approximator property of neural networks, in particular (Hornik, 1990) form the basis underlying this assumption. It is critical for industrial applications of inferential sensors because it gives the necessary theoretical basis for reliable predictions and to support the investment for model development. The third assumption is the expectations of performance deterioration in new operating conditions (i.e., outside the range of training data), which is a logical consequence from the previous two assumptions. As a result, model retraining or even a complete redesign is recommended. Since the process and operating condition variations are rather a rule than an exception, increased robustness in these circumstances becomes the central issue of inferential sensor design.

Slepian Wolf coding. Correlated sources X and Y can be described separately at rates R1 and R2 and recovered with arbitrarily low probability of error by a common decoder if and only if R1 H (X|Y ), R2 H (Y |X), R1 + R2 H (X, Y ). (15.354) (15.355) (15.356)

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