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hydrophobic residues has become charged and very hydrophilic The result is that phosphorylation can induce dramatic changes to a protein s conformation In its initial state (left side of Fig 11-12) the protein s conformation is such that its three sodium binding sites and two potassium binding sites are exposed to the inside of the cell In this conformation, the Gibbs energy change for binding ATP and for binding sodium ions is highly negative (favorable) At the same time, potassium binding is not energetically favorable So the protein quickly binds ATP plus any free sodium ions that are nearby Once three sodium ions are bound, the protein undergoes a slight conformational change that allows it to hydrolyze ATP The ATP hydrolysis results in phosphorylation of the sodiumpotassium pump This in turn, as we mentioned, changes the Gibbs energy interactions that determine the secondary and tertiary structure of the pump The phosphorylated form of the protein has a dramatically different conformation and a dramatically different affinity for binding sodium and potassium In its new conformation (second illustration from the left in Fig 11-12) the sodium and potassium binding sites are now exposed to the outside of the cell But the Gibbs energy change for binding sodium ions is now positive (unfavorable) This means that releasing the sodium ions provides a negative (favorable) Gibbs energy change So the three sodium ions are quickly released to the outside of the cell All of this is the result of the changes in location of the various charges, polar groups, hydrogen bonds, and hydrophobic residues in the protein, due to the phosphorylation and accompanying conformational change

Note: The TextAlign property takes its values from the ToolBarTextAlign enumeration, with possible values Underneath and Right. The default is Underneath.

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As you can see, the Dock property of a ToolBar is set to Top by default. Visual Studio also sets the DropDownArrows and ShowToolTips properties to true, even though the default for both settings is false. The code generated here is nothing unusual, so we will move on to the ToolBarButton class. 13.1.3 THE TOOLBARBUTTON CLASS By themselves, toolbars do not present much information to the user. These objects take on meaning and purpose once they have one or more toolbar buttons placed on them. In this section we look at the ToolBarButton class in some detail. We will hold off discussing exactly how to place our buttons on the toolbar until section 13.3, after we have introduced the idea of an image list in section 13.2. An overview of the ToolBarButton class appears in .NET Table 13.2. This object is a component, so it does not inherit any properties from the Control class. As a result, a number of control-like properties such as Enabled, Tag, and Visible are defined explicitly by this class. 413

The ToolBarButton class represents a button that appears within a toolbar control. These buttons typically provide shortcuts to menu commands and other commonly used tasks for the associated form. This class is part of the System.Windows.Forms namespace, and inherits from the System.ComponentModel.Component class. DropDownMenu Gets or sets the Menu object to display as the menu for a button with a dropdown style. While this property is of type Menu, a ContextMenu instance should normally be provided. Gets or sets whether this button is active. Gets or sets the index into the parent toolbar s ImageList property to display on this button. Gets the ToolBar object containing this toolbar button. Gets or sets whether a button with a toggle style is displayed as partially pushed. Gets or sets whether a button with a toggle style is displayed as pushed. Gets the bounding rectangle for the toolbar button. Gets or sets the display style for this button. Gets or sets an object instance to associate with this toolbar button. Gets or sets the text string to display on the button. Gets or sets the tool tip string to associate with the button. Gets or sets whether the button is shown on the toolbar.

Computer Science Department, University of Bologna Synthetic Fingerprint Generator (SfinGe) Home Version 25 September 4, 2002 http:// biascsruniboit/research/biolab/sfingehtml Daugman, J United States Patent No 5,291,560 (issued 1 March 1994) Biometric Personal Identification System Based on Iris Analysis Washington DC: US Government Printing Office Fejfar, A, and W Haberman Automatic Identification of Personnel Through Speaker and Signature Verification System Description and Testing Proceedings of Carnahan Conference on Crime Countermeasures July 1977 Oxford, UK Jain, Anil, Sharath Pankanti, and Salil Prabhakar On the Individuality of Fingerprints 2001 Michigan State University IBM Research Center Digital Persona, Inc Mansfield, T, G Kelly, D Chandler, and J Kane Biometric Product Testing Final Report The National Physical Laboratory (NPL), Centre for Mathematics and Scientific Computing 2001 Middlesex, United Kingdom Phillips, P J, et al Face Recognition Vendor Test 2002 http://wwwfrvtorg/ FRVT2002/defaulthtm Phillips, P J, et al FRVT 2000 Evaluation Report Department of Defense Counterdrug Technology Development Program Office http://wwwfrvtorg/ FRVT2000/documentshtm Phillips, P J, P Rauss, and S Der FacE REcognition Technology (FERET) Recognition Algorithm Development and Test Report, ARL-TR-995 1996 United States Army Research Laboratory Underwriters Laboratories, Inc http://wwwulcom

Enabled ImageIndex Parent PartialPush Pushed Public Properties Rectangle Style Tag Text ToolTipText Visible

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